HIE Calculator

Welcome to the Florida Neonatal Neurologic Network HIE Calculator! The calculator is based on the algorithm developed by the NICHD in the publication by Namasivyam Ambalavanan[1]. This calculator is designed to serve as a clinical tool for the bedside clinician and should not be the sole factor to make clinical decisions. The calculator should be performed in the first 6 hours of life.


Death/Disability Calculator

What is the posture of the baby on the initial exam?

What spontaneous activity does the baby display on the initial exam?

What was the base deficit of the first postnatal blood gas?

What was the Apgar score at 5 minutes?

Was chronic hypertension or pre-eclampsia or eclampsia present in the mother?

Score Scale

Less than 23: No death or moderate/severe disability even without hypothermia

23-28: Probable benefit from hypothermia

29-52: Possible benefit from hypothermia

Greater than 52: Death/Disability likely despite hypothermia


Death Calculator

What is the posture on the initial neurologic exam?

What is the quality of the suck on the initial exam?

Was there an antepartum hemorrhage?

What was the base deficit on the first postnatal blood gas?

Score Scale

Less than 8: Survival even without hypothermia

8-15: Probable benefit from hypothermia

16-30: Possible benefit from hypothermia

Greater than 30: Death likely despite hypothermia


1. Ambalavanan, N., et al., Predicting outcomes of neonates diagnosed with hypoxemic-ischemic encephalopathy. Pediatrics, 2006. 118(5): p. 2084-93.